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Defeating cancer: the most important questions in cancer research and clinical oncology.
For example, some acquired secondary mutations, e. The genomic landscape of this subtype remains unclear. Such biomarkers may be susceptible to detect mutations at the genetic or epigenetic level, identifying important non-coding RNA especially microRNA and long non-coding RNAproviding insights regarding the metabolic profiles, estimating the tumor level in liquid biopsies circulating free DNA, circulating tumor cells and exosomesand so on.
Affiliation and emails Crown Biosciences Inc. Initiation is thought to be the first step of the multistep model of cancer development, followed by promotion and progression.
This alteration is also named tumor evolution, which partially explains acquired drug resistance.
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